Phenolphthalein is commonly used as a chemical indicator, which turns from colorless to pink in the range of 8–10 pH, which makes it ideal for the titration of strong acids, such as hydrochloric acid. | Blog about Cheméo's technical and scientific challenges, Blog about Cheméo's technical and scientific challenges, .alpha, alpha.-Di(p-hydroxyphenyl)phthalide, 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxyphenyl)-, 3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone, 3,3-Bis(4-hydroxyphenyl)-2-benzofuran-1(3h)-one. CAS Number: 77-09-8 Formula: C20H14O4 Density: 1.299 g/mL Solubility: Alcohol and Alkalis Shelf Life: 36 Months. Phenolphthalein is absorbed in the intestine and is almost completely converted to its glucuronide during extensive first-pass metabolism in the intestinal epithelium and liver via uridine diphosphate glucuronosyltransferase (UDPGT) in rodents and dogs. A light pink color of the phenolphthalein is aimed in this experiment. Predict Chemical & Physical Properties Find more compounds similar to Phenolphthalein. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. It is available in the form of an oral solution, oral capsule, oral tablet, wafer and chewing gum. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in … Find patient medical information for Phenolphthalein, Yellow Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Phenolphthalein is also prescribed for the treatment of chronic atonic or spastic constipation and of constipation associated with rectal disorders; management of irritable bowel syndrome. Odor No odor. It is usually administered orally. Phenolphthalein, (C 20 H 14 O 4), an organic compound of the phthalein family that is widely employed as an acid - base indicator. Public notices related to this chemical: 2012 Priority List for the Development of Proposition 65 NSRLs for Carcinogens and MADLs for Chemicals Causing Reproductive Toxicity; 27 Chemicals Listed Effective May 15, 1998 as Known to the State to Cause Cancer or … Phenolphthalein (PTH), which has been used as the active ingredient in a number of prescription and over-the-counter laxative products, is a rodent chemical carcinogen in multiple organs in the NTP 2-year bioassay at doses of 291-2927 mg/kg. Molecular weight 318.33. Phenolphthalein. Take the time to validate and double check the source of the data. Phenolphthalein is often used as an indicator in acid–base titrations. Phenolphthalein was widely used as a laxativ… 2012 Priority List for the Development of Proposition 65 NSRLs for Carcinogens and MADLs for Chemicals Causing Reproductive Toxicity; 27 Chemicals Listed Effective May 15, 1998 as Known to the State to Cause Cancer or … Download as PDF file The reagent for these acid-base titrations is prepared at 1% dissolved in 90% alcohol. When dissolved in alcohol solution, it can be made of acid and alkali indicator. As an indicator of a solution’s pH, phenolphthalein is colourless below pH 8.5 and attains a pink to deep red hue above pH 9.0. It is a weak aci.... (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), 3,3-Bis(4-hydroxyphenyl)phthalide (77-09-8), P210-P260-P280a-P303+P361+P353-P405-P501a-P201-P202-P280-P308+P313, 40-22-10-36/38-23/25-11-36/37/38-68-62-45-39/23/24/25-23/24/25, Phenolphthalein (0.1% in ca. Appearance White powder. Blood. The Hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents.The information in CAMEO Chemicals comes from a variety of data sources. In acidic solutions, the compound is colourless. Chemicals for Science Education. Reference substance name: Phenolphthalein EC Number: 201-004-7 EC Name: Phenolphthalein CAS Number: 77-09-8 Molecular formula: C20H14O4 IUPAC Name: 3,3-bis(4-hydroxyphenyl)-1,3-dihydro-2-benzofuran-1-one But if used over a prolonged period of time, it can cause imbalances in your body’s electrolyte levels, weakness, and an increased incidence of falls. 8 Kuwabara, Tetsuo et al. Melting Point 262°C. Public Notices Related to this Chemical. The physical properties of these compounds result directly from the formation of hydrogen bonds and are manifested in relatively high b.p., high viscosity, and their water solubility. It belongs to the class of dyes known as phthalein dyes. Chemical Properties of Phenolphthalein (CAS 77-09-8) Download as PDF file Download as Excel file Download as 2D mole file Predict properties No: F/QCL/008 Rev.01 PT.SMART-LAB INDONESIA MSDS – PHENOLPHTHALEIN INDICATOR 1 MATERIAL SAFETY DATA SHEET PHENOLPHTHALEIN INDICATOR Revision : 01 Date of Issue: 16.05.2017 MSDS Number : 152 Section 1 - Chemical Product and Company Identification +Add Attachment Weight Average: 318.3228 Monoisotopic: 318.089208936 Chemical Formula C 20 H 14 O 4 Synonyms. (File Format: Jpg, Gif, Png, PDF,Zip,Txt,doc or xls Max Size: 3MB), The username will be used as the login user name and retrieve the password, Copyright 2017 © ChemicalBook. In such cases, it is used to empty the bowels. Structure, properties, spectra, suppliers and links for: Phenolphthalein, 77-09-8. Solubility Soluble in alcohol and alkalis. Predict properties. Phenolphthalein is used in chemical analysis as a visual indicator in the determination of the equivalence point in neutralization reactions or acid-base titrations. PHYSICAL PROPERTIES OF PHENOLPHTHALEIN Page in - The World's Leading Industrial Portal, offering Business Tools and Information. Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. 3,3-Bis(4-hydroxyphenyl)phthalide; Fenolftalein Phenolphthalein is a slightly acidic compound, hence considered a weak acid. © 2016 Céondo GmbH | It has traditionally been used as a laxative but has more recently been used as part of a test to Pricing & More Info Phenolphthalein Indicator, … Note: Cheméo is only indexing the data, follow the source links to retrieve the latest data. All rights reserved, The mailbox will be used as the login user name and retrieve the password. Phenolphthalein-Modified β-Cyclodextrin as a Molecule-Responsive Colorless-to-Color Change Indicator. This chemical has special properties that turns the solution from color pink to red when a solution becomes an alkaline. Phenolphthalein has the chemical formula of C 20 H 14 O 4 and is a large organic molecule. The test item has a mean melting point of 263.7 °C. Phenolphthalein is used as a laxative to treat incomplete and infrequent bowel movement. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. Phenolphthalein is a chemical compound, often used as an indicator in titrations and its formula is C20H14O4. The phenolphthalein structure is a is good example of a C3 Point Group & shows "propeller" rotation. JOC 1998 , 63, 8729–8735. Safety Data Sheet according to 29CFR1910/1200 and GHS Rev. Download as Excel file Chemical Properties Phenolphthalein is a weak organic acid, at room temperature, appearing as white or microstrip yellow small crystals, being odorless, tasteless, insoluble in water and soluble in alcohol (ethanol) and ether. Phenolphthalein, an organic compound with the chemical formula C20H14O4, is a weak acid which can be used as an indicator for acid-base titrations. Chemical data; Molecular Weight Formula; 318.3282: Note: The chemical specifications for some items on this product page may differ from the specifications listed above. The source is also providing more information like the publication year, authors and more. Odor Threshold N/A. Allan R. De Jong MD, in Child Abuse and Neglect, 2011. OSHA Vacated PELs: Phenolphthalein: No OSHA Vacated PELs are listed for this chemical. In crystalline form, phenolphthalein appears to be white to yellow in colour. Information on Registered Substances comes from registration dossiers which have been assigned a registration number. 3 Effective date : 01.14.2015 Page 2 of 8 Phenolphthalein Indicator Created by Global Safety Management, Inc. -Tel: 1-813-435-5161 - Phenolphthalein is a chemical compound with the formula C20H14O4 and is often written as "HIn" or "phph" in shorthand notation. Chemical and physical properties of Phenolphthalein. 90% Ethanol) [for Titration], .alpha, alpha.-Di(p-hydroxyphenyl)phthalide, 1(3H)-Isobenzofuranone, 3,3-bis(4-hydroxyphenyl)-, 1(3H)-Isobenzofuranone,3,3-bis(4-hydroxyphenyl)-, 3,3-bis(4-hydroxyphenyl)-1(3h)-isobenzofuranon, alpha-(p-hydroxyphenyl)-alpha-(4-oxo-2,5-cyclohexadien-1-ylidine)-o-toluicacid, 3,3-BIS(4-HYDROXYPHENYL)-1(3H)-ISOBENZOFURANONE, 3,3-Bis(4-hydroxyphenyl)-1(3H)-isobenzofuranone, Phenolphthaleinum. Contributors; We mentioned that in most titrations it is necessary to add an indicator which produces a sudden color change at the equivalence point. It is pinkish in simple solutions (with the transition occurring around pH 9). For this application, it turns colorless in acidic solutions and pink in basic solutions. How does phenolphthalein function as an indicator? Phenolphthalein (C 20 H 14 O 4).An indicator used in the solution. Phenolphthalein, Powder, Reagent, ACS is a chemical compound that varies in color according to the acidity level of the solution it is in. Specific Gravity 1.30 g/mL @ 20°C. MSDS # 525.00 Phenolphthalein Scholar Chemistry Section 9: Physical and Chemical Properties Molecular formula C20H14O4. Vapor Density (air=1) N/A. Find patient medical information for Phenolphthalein Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The melting point of Phenolphthalein was investigated in an OECD guideline 102 compliant study. In terms of chemical properties, they are typical of other alcohols and are specific because of the presence of two hydroxyl groups on adjacent carbon atoms. It was discovered in 1871 by German chemist Adolf von Baeyer & was commonly used as laxative until it was discovered to be a carcinogen. Phenolphthalein has 4 states: - In a strongly acid medium it has an orange color (H 3 In +). Download as 2D mole file